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The ciliary muscle is an intrinsic muscle of the Human eye formed as a ring of smooth muscleSchachar, Ronald A. (2012). "Anatomy and Physiology." (Chapter 4) . in the eye's middle layer, the uvea (vascular layer). It controls accommodation for viewing objects at varying distances and regulates the flow of aqueous humor into Schlemm's canal. It also changes the shape of the lens within the eye but not the size of the pupil which is carried out by the sphincter pupillae muscle and dilator pupillae.
The ciliary muscle, pupillary sphincter muscle and pupillary dilator muscle sometimes are called intrinsic ocular muscles or intraocular muscles.
Presynaptic parasympathetic signals that originate in the Edinger-Westphal nucleus are carried by cranial nerve III (the oculomotor nerve) and travel through the ciliary ganglion via the postganglionic parasympathetic fibers which travel in the short ciliary nerves and supply the ciliary body and iris. Parasympathetic activation of the M3 muscarinic receptors causes ciliary muscle contraction. The effect of contraction is to decrease the diameter of the ring of ciliary muscle causing relaxation of the zonule fibers, the lens becomes more spherical, increasing its power to refract light for near vision.
The parasympathetic tone is dominant when a higher degree of accommodation of the lens is required, such as reading a book. (2025). 9780071624428, McGraw-Hill. ISBN 9780071624428
According to Hermann von Helmholtz's theory, the circular ciliary muscle fibers affect zonular fibers in the human eye (fibers that suspend the lens in position during accommodation), enabling changes in lens shape for light focusing. When the ciliary muscle contracts, it pulls itself forward and moves the frontal region toward the axis of the eye. This releases the tension on the lens caused by the zonular fibers (fibers that hold or flatten the lens). This release of tension of the zonular fibers causes the lens to become more spherical, adapting to short range focus. Conversely, relaxation of the ciliary muscle causes the zonular fibers to become taut, flattening the lens, increasing the focal distance,
==Additional images==
(2025). 9780071624428, McGraw-Hill. ISBN 9780071624428 increasing long range focus. Although Helmholtz's theory has been widely accepted since 1855, its mechanism still remains controversial. Alternative theories of accommodation have been proposed by others, including L. Johnson, M. Tscherning, and especially Ronald A. Schachar.
Trabecular meshwork pore size
Contraction and relaxation of the longitudinal fibers, which insert into the trabecular meshwork in the anterior chamber of the eye, cause an increase and decrease in the meshwork pore size, respectively, facilitating and impeding aqueous humour flow into the canal of Schlemm.Salmon John F, "Chapter 11. Glaucoma" (Chapter). AccessMedicine.com
Clinical significance
Glaucoma
Open-angle glaucoma (OAG) and closed-angle glaucoma (CAG) may be treated by muscarinic receptor agonists (e.g., pilocarpine), which cause rapid miosis and contraction of the ciliary muscles, opening the trabecular meshwork, facilitating drainage of the aqueous humour into the canal of Schlemm and ultimately decreasing intraocular pressure.Le, Tao T.; Cai, Xumei; Waples-Trefil, Flora. "QID: 22067". USMLERx. MedIQ Learning, LLC. 2006–2010. 13 January 2010 Usmlerx.com
History
Etymology
The word ciliary had its origins around 1685–1695."cilia", Unabridged. Source location: Random House, Inc. Reference.com. Retrieved on 2010-01-16 from http://dictionary.reference.com/browse/cilia. The term cilia originated a few years later in 1705–1715, and is the Neo-Latin plural of cilium meaning eyelash. In Latin, cilia means upper eyelid and is perhaps a back formation from supercilium, meaning eyebrow. The suffix -ary originally occurred in loanwords from Middle English ( -arie), Old French ( -er, -eer, -ier, - aire, -er), and Latin ( -ārius); it can generally mean "pertaining to, connected with", "contributing to", and "for the purpose of".Dictionary.com, "-ary", in The American Heritage Dictionary of the English Language, Fourth Edition. Source location: Houghton Mifflin Company, 2004. Reference.com. Retrieved on 2010-01-16 from http://dictionary.reference.com/browse/-ary. Taken together, cili(a)-ary pertains to various anatomical structures in and around the eye, namely the ciliary body and annular suspension of the lens of the eye."ciliary," in Dictionary.com Unabridged. Source location: Random House, Inc. Reference.com. Retrieved on 2010-01-16 from http://dictionary.reference.com/browse/ciliary.
See also
External links
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